Super Tadapox is marketed as a combination of tadalafil and dapoxetine. Tadalafil is a PDE-5 inhibitor used for erectile dysfunction (ED), while dapoxetine is an SSRI used to help manage premature ejaculation. Because tadalafil can lower blood pressure, chest pain while taking the medicine requires prompt medical attention.

Chest pain may indicate a serious cardiovascular problem, such as angina or a heart attack. Sexual activity itself increases the heart's workload, so chest pain during or after sexual activity should never be assumed to be a harmless side effect.

There is another critical concern: people experiencing chest pain may be given nitrate medicines, such as nitroglycerin. These medicines must not be combined with tadalafil. Tadalafil can enhance the blood-pressure-lowering effects of nitrates, potentially causing a severe and dangerous drop in blood pressure.

If chest pain develops after taking Super Tadapox, stop sexual activity and seek emergency medical care. Tell healthcare professionals that you have taken tadalafil and when you took it. Do not take nitroglycerin or other nitrate medication unless emergency clinicians specifically determine it is safe.

Other emergency symptoms—including severe dizziness, fainting, difficulty breathing, sudden vision or hearing loss, or an erection lasting more than four hours—also require urgent evaluation.

For safety, never combine Super Tadapox with other ED medicines or change its dose without medical advice.